Binding Affinity Protein Stability

Monolith X with breakthrough Spectral Shift Technology


With Monolith X, you’ll get Spectral Shift and MST — two biophysical modalities to help cover all the types of interactions you encounter. You’ll enjoy high-quality results without spending your time on assay development and finally perform experiments without worrying about sample aggregation or impurities.

Many great ways to use Monolith

  • Validate your SPR results with an immobilization-free method
  • Work with challenging interactions that are difficult for SPR
  • Use a versatile tool to tackle a wide variety of projects

Standard Features

  • Capture measurements in minutes not hours or even days. Collect more information and make better decisions on what to do next, sooner.
  • Easily measure binding interactions between molecules of different sizes, molecular weights or pM to mM binding affinities.
  • Generating sample is already hard enough and using it all up for analysis is heartbreaking. Get Kd values with just a tiny amount of sample.
  • Saving a bit of time here and there adds up so the less time prepping samples, the better. Analyze samples in any buffer or bioliquid and in close-to-native conditions. OH, and purification or immobilization isn't needed either.
  • Feedback is immediate and doesn't take days or weeks to get up and running—this makes optimizing assays so much easier.
  • Running into a roadblock? Get results even when other methods don't work.

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